BhaktisiddhantaBimala Prasad was born in 1874 in Puri (Orissa) a son of Kedarnath Datta Bhaktivinoda Thakur, a recognised Bengali Gaudiya Vaishnava philosopher and teacher. Bimala Prasad received both Western and traditional Indian education and gradually established himself as a leading intellectual among the bhadralok (Western-educated and often Hindu Bengali residents of colonial Calcutta), earning the title Siddhanta Sarasvati ("the pinnacle of wisdom"). Under the direction of his father and spiritual preceptor, Bimala Prasad took initiation (diksha) into Gaudiya Vaishnavism from the Vaishnava

ascetic Gaurakishora Dasa Babaji, receiving the name Shri Varshabhanavi-devi-dayita Dasa (Śrī Vārṣabhānavī-devī-dayita Dāsa, "servant of Krishna, the beloved of Radha"), and dedicated himself to arduous ascetic discipline, recitation of the Hare Krishna mantra on beads (japa), and study of classical Vaishnava literature.

After the deaths of his father and his guru, in 1918 Bimala Prasad accepted the Hindu formal order of asceticism (sannyasa), becoming known as Bhaktisiddhanta Sarasvati Goswami. In the same year Bhaktisiddhanta Sarasvati inaugurated in Calcutta the first center of his institution, later known as the Gaudiya Math. It soon developed into a dynamic missionary and educational institution with sixty-four branches across India and three centres abroad (in Burma, Germany, and England). The Math propagated the teachings of Gaudiya Vaishnavism by means of daily, weekly, and monthly periodicals, books of the Vaishnava canon, and public programs as well as through such innovations as "theistic exhibitions" with dioramas. Known for his intense and outspoken oratory and writing style as the "acharya-keshari" ("lion guru"). Bhaktisiddhanta opposed themonistic interpretation of Hinduism, or advaita, that had emerged as the prevalent strand of Hindu thought in India, seeking to establish traditional personalist krishna-bhakti as its fulfilment and higher synthesis. At the same time, through lecturing and writing, Bhaktisiddhanta Sarasvati targeted both the ritualistic casteism of smarta brahmanas and sensualised practices of numerous Gaudiya Vaishavism spin-offs , branding them asapasampradayas – deviations from the original Gaudiya Vaishnavism taught in the 16th century by Caitanya Mahaprabhu and his close successors.